# Biotechnology machines - Stage 4 (technology) internal name `biotech-machines-mk04` · tier 10 (Space science pack, [tier 10](https://factorio.kalzumeus.com/tier/10.md)) HTML page: https://factorio.kalzumeus.com/tech/biotech-machines-mk04/ ## Cost 3600 units of (1 × [Space science pack](https://factorio.kalzumeus.com/item/space-science-pack.md), 2 × [Utility science pack](https://factorio.kalzumeus.com/item/utility-science-pack.md), 3 × [pY science pack 4](https://factorio.kalzumeus.com/item/py-science-pack-4.md), 6 × [Production science pack](https://factorio.kalzumeus.com/item/production-science-pack.md), 10 × [pY science pack 3](https://factorio.kalzumeus.com/item/py-science-pack-3.md), 20 × [Chemical science pack](https://factorio.kalzumeus.com/item/chemical-science-pack.md), 30 × [pY science pack 2](https://factorio.kalzumeus.com/item/py-science-pack-2.md), 60 × [Logistic science pack](https://factorio.kalzumeus.com/item/logistic-science-pack.md), 100 × [pY science pack 1](https://factorio.kalzumeus.com/item/py-science-pack-1.md), 200 × [Automation science pack](https://factorio.kalzumeus.com/item/automation-science-pack.md), 30 × [Military science pack](https://factorio.kalzumeus.com/item/military-science-pack.md)), 1200 s each. ## Requires (2) - [Biotechnology machines - Stage 3](https://factorio.kalzumeus.com/tech/biotech-machines-mk03.md) - [Quantum computing](https://factorio.kalzumeus.com/tech/space-science-pack.md) ## Leads to (2) - [Atomizer upgrade](https://factorio.kalzumeus.com/tech/atomizer-upgrade.md) - [Pyrrhic victory](https://factorio.kalzumeus.com/tech/pyrrhic.md) ## Unlocks (13 recipes) ### Atomizer MK 04 (`atomizer-mk04`) - 4 s · tier 10 - Ingredients: 1 × [Atomizer MK 03](https://factorio.kalzumeus.com/item/atomizer-mk03.md), 10 × [Intelligent unit](https://factorio.kalzumeus.com/item/intelligent-unit.md), 40 × [Super steel](https://factorio.kalzumeus.com/item/super-steel.md), 30 × [Super alloy](https://factorio.kalzumeus.com/item/super-alloy.md), 10 × [Nanoelectromechanical systems](https://factorio.kalzumeus.com/item/nems.md), 100 × [Phosphate glass](https://factorio.kalzumeus.com/item/phosphate-glass.md), 10 × [Quantum vortex storage system](https://factorio.kalzumeus.com/item/quantum-vortex-storage-system.md), 10 × [Metastable Quasicrystal](https://factorio.kalzumeus.com/item/metastable-quasicrystal.md), 3 × [Superconducting Claw-pole Engine](https://factorio.kalzumeus.com/item/sc-engine.md), 1 × [Mechanical Parts 04](https://factorio.kalzumeus.com/item/mechanical-parts-04.md) - Results: 1 × [Atomizer MK 04](https://factorio.kalzumeus.com/item/atomizer-mk04.md) - Made in: Burner assembling machine MK 01, Burner assembling machine MK 02, Burner assembling machine MK 03, Automated factory MK 01, Automated factory MK 02, Automated factory MK 03, Automated factory MK 04, Character, Character (flying), Mutagenic infusion, (flying) - Unlocked by: [Biotechnology machines - Stage 4](https://factorio.kalzumeus.com/tech/biotech-machines-mk04.md) ### Bioreactor MK 04 (`bio-reactor-mk04`) - 4 s · tier 10 - Ingredients: 1 × [Bioreactor MK 03](https://factorio.kalzumeus.com/item/bio-reactor-mk03.md), 50 × [Kevlar](https://factorio.kalzumeus.com/item/kevlar.md), 30 × [Super alloy](https://factorio.kalzumeus.com/item/super-alloy.md), 60 × [Super steel](https://factorio.kalzumeus.com/item/super-steel.md), 10 × [Control unit](https://factorio.kalzumeus.com/item/control-unit.md), 1 × [Blanket](https://factorio.kalzumeus.com/item/blanket.md), 30 × [Hyperelastic material](https://factorio.kalzumeus.com/item/hyperelastic-material.md), 10 × [Nitrogen vacancy center](https://factorio.kalzumeus.com/item/nv-center.md), 5 × [Metastable Quasicrystal](https://factorio.kalzumeus.com/item/metastable-quasicrystal.md), 1 × [Superconducting Claw-pole Engine](https://factorio.kalzumeus.com/item/sc-engine.md), 1 × [Mechanical Parts 04](https://factorio.kalzumeus.com/item/mechanical-parts-04.md) - Results: 1 × [Bioreactor MK 04](https://factorio.kalzumeus.com/item/bio-reactor-mk04.md) - Made in: Burner assembling machine MK 01, Burner assembling machine MK 02, Burner assembling machine MK 03, Automated factory MK 01, Automated factory MK 02, Automated factory MK 03, Automated factory MK 04, Character, Character (flying), Mutagenic infusion, (flying) - Unlocked by: [Biotechnology machines - Stage 4](https://factorio.kalzumeus.com/tech/biotech-machines-mk04.md) ### Biofactory MK 04 (`biofactory-mk04`) - 1 s · tier 10 - Ingredients: 1 × [Biofactory MK 03](https://factorio.kalzumeus.com/item/biofactory-mk03.md), 30 × [Iron niobium alloy](https://factorio.kalzumeus.com/item/nbfe-alloy.md), 25 × [NENBIT matrix](https://factorio.kalzumeus.com/item/nenbit-matrix.md), 40 × [Boron carbide](https://factorio.kalzumeus.com/item/boron-carbide.md), 10 × [Control unit](https://factorio.kalzumeus.com/item/control-unit.md), 100 × [Super steel](https://factorio.kalzumeus.com/item/super-steel.md), 15 × [Harmonic absorber](https://factorio.kalzumeus.com/item/harmonic-absorber.md), 15 × [Intelligent unit](https://factorio.kalzumeus.com/item/intelligent-unit.md), 20 × [Sub denier microfiber](https://factorio.kalzumeus.com/item/sub-denier-microfiber.md), 5 × [Metastable Quasicrystal](https://factorio.kalzumeus.com/item/metastable-quasicrystal.md), 1 × [Superconducting Claw-pole Engine](https://factorio.kalzumeus.com/item/sc-engine.md), 1 × [Mechanical Parts 04](https://factorio.kalzumeus.com/item/mechanical-parts-04.md) - Results: 1 × [Biofactory MK 04](https://factorio.kalzumeus.com/item/biofactory-mk04.md) - Made in: Burner assembling machine MK 01, Burner assembling machine MK 02, Burner assembling machine MK 03, Automated factory MK 01, Automated factory MK 02, Automated factory MK 03, Automated factory MK 04, Character, Character (flying), Mutagenic infusion, (flying) - Unlocked by: [Biotechnology machines - Stage 4](https://factorio.kalzumeus.com/tech/biotech-machines-mk04.md) ### Compost plant MK 04 (`compost-plant-mk04`) - 4 s · tier 10 - Ingredients: 1 × [Compost plant MK 03](https://factorio.kalzumeus.com/item/compost-plant-mk03.md), 100 × [Super steel](https://factorio.kalzumeus.com/item/super-steel.md), 50 × [Boron carbide](https://factorio.kalzumeus.com/item/boron-carbide.md), 10 × [Control unit](https://factorio.kalzumeus.com/item/control-unit.md), 20 × [Metallic glass](https://factorio.kalzumeus.com/item/metallic-glass.md), 40 × [NENBIT matrix](https://factorio.kalzumeus.com/item/nenbit-matrix.md), 30 × [Advanced coating](https://factorio.kalzumeus.com/item/science-coating.md), 10 × [Metastable Quasicrystal](https://factorio.kalzumeus.com/item/metastable-quasicrystal.md), 3 × [Superconducting Claw-pole Engine](https://factorio.kalzumeus.com/item/sc-engine.md), 1 × [Mechanical Parts 04](https://factorio.kalzumeus.com/item/mechanical-parts-04.md) - Results: 1 × [Compost plant MK 04](https://factorio.kalzumeus.com/item/compost-plant-mk04.md) - Made in: Burner assembling machine MK 01, Burner assembling machine MK 02, Burner assembling machine MK 03, Automated factory MK 01, Automated factory MK 02, Automated factory MK 03, Automated factory MK 04, Character, Character (flying), Mutagenic infusion, (flying) - Unlocked by: [Biotechnology machines - Stage 4](https://factorio.kalzumeus.com/tech/biotech-machines-mk04.md) ### Creature chamber MK 04 (`creature-chamber-mk04`) - 1 s · tier 10 - Ingredients: 1 × [Creature chamber MK 03](https://factorio.kalzumeus.com/item/creature-chamber-mk03.md), 30 × [Advanced coating](https://factorio.kalzumeus.com/item/science-coating.md), 30 × [Silver zinc alloy](https://factorio.kalzumeus.com/item/agzn-alloy.md), 20 × [Silver foam](https://factorio.kalzumeus.com/item/silver-foam.md), 30 × [Low density structure](https://factorio.kalzumeus.com/item/low-density-structure.md), 5 × [Control unit](https://factorio.kalzumeus.com/item/control-unit.md), 100 × [Neodymium magnet](https://factorio.kalzumeus.com/item/re-magnet.md), 100 × [Phosphate glass](https://factorio.kalzumeus.com/item/phosphate-glass.md), 30 × [Hyperelastic material](https://factorio.kalzumeus.com/item/hyperelastic-material.md), 8 × [Metastable Quasicrystal](https://factorio.kalzumeus.com/item/metastable-quasicrystal.md), 3 × [Superconducting Claw-pole Engine](https://factorio.kalzumeus.com/item/sc-engine.md), 1 × [Mechanical Parts 04](https://factorio.kalzumeus.com/item/mechanical-parts-04.md) - Results: 1 × [Creature chamber MK 04](https://factorio.kalzumeus.com/item/creature-chamber-mk04.md) - Made in: Burner assembling machine MK 01, Burner assembling machine MK 02, Burner assembling machine MK 03, Automated factory MK 01, Automated factory MK 02, Automated factory MK 03, Automated factory MK 04, Character, Character (flying), Mutagenic infusion, (flying) - Unlocked by: [Biotechnology machines - Stage 4](https://factorio.kalzumeus.com/tech/biotech-machines-mk04.md) ### Flora collector MK 04 (`flora-collector-mk04`) - 5 s · tier 10 - Ingredients: 1 × [Flora collector MK 03](https://factorio.kalzumeus.com/item/flora-collector-mk03.md), 20 × [Advanced coating](https://factorio.kalzumeus.com/item/science-coating.md), 5 × [Divertor](https://factorio.kalzumeus.com/item/divertor.md), 5 × [Control unit](https://factorio.kalzumeus.com/item/control-unit.md), 10 × [Metallic glass](https://factorio.kalzumeus.com/item/metallic-glass.md), 30 × [Boron carbide](https://factorio.kalzumeus.com/item/boron-carbide.md), 8 × [Harmonic absorber](https://factorio.kalzumeus.com/item/harmonic-absorber.md), 10 × [Hyperelastic material](https://factorio.kalzumeus.com/item/hyperelastic-material.md), 2 × [Intelligent unit](https://factorio.kalzumeus.com/item/intelligent-unit.md), 2 × [Metastable Quasicrystal](https://factorio.kalzumeus.com/item/metastable-quasicrystal.md), 2 × [Superconducting Claw-pole Engine](https://factorio.kalzumeus.com/item/sc-engine.md), 2 × [Mechanical Parts 04](https://factorio.kalzumeus.com/item/mechanical-parts-04.md) - Results: 1 × [Flora collector MK 04](https://factorio.kalzumeus.com/item/flora-collector-mk04.md) - Made in: Burner assembling machine MK 01, Burner assembling machine MK 02, Burner assembling machine MK 03, Automated factory MK 01, Automated factory MK 02, Automated factory MK 03, Automated factory MK 04, Character, Character (flying), Mutagenic infusion, (flying) - Unlocked by: [Biotechnology machines - Stage 4](https://factorio.kalzumeus.com/tech/biotech-machines-mk04.md) ### Gene lab MK 04 (`genlab-mk04`) - 1 s · tier 10 - Ingredients: 1 × [Gene lab MK 03](https://factorio.kalzumeus.com/item/genlab-mk03.md), 40 × [NENBIT matrix](https://factorio.kalzumeus.com/item/nenbit-matrix.md), 10 × [Intelligent unit](https://factorio.kalzumeus.com/item/intelligent-unit.md), 100 × [Kevlar](https://factorio.kalzumeus.com/item/kevlar.md), 10 × [Divertor](https://factorio.kalzumeus.com/item/divertor.md), 30 × [Low density structure](https://factorio.kalzumeus.com/item/low-density-structure.md), 5 × [Nanoelectromechanical systems](https://factorio.kalzumeus.com/item/nems.md), 15 × [Graphene roll](https://factorio.kalzumeus.com/item/graphene-roll.md), 10 × [Nitrogen vacancy center](https://factorio.kalzumeus.com/item/nv-center.md), 4 × [Metastable Quasicrystal](https://factorio.kalzumeus.com/item/metastable-quasicrystal.md), 1 × [Superconducting Claw-pole Engine](https://factorio.kalzumeus.com/item/sc-engine.md), 1 × [Mechanical Parts 04](https://factorio.kalzumeus.com/item/mechanical-parts-04.md) - Results: 1 × [Gene lab MK 04](https://factorio.kalzumeus.com/item/genlab-mk04.md) - Made in: Burner assembling machine MK 01, Burner assembling machine MK 02, Burner assembling machine MK 03, Automated factory MK 01, Automated factory MK 02, Automated factory MK 03, Automated factory MK 04, Character, Character (flying), Mutagenic infusion, (flying) - Unlocked by: [Biotechnology machines - Stage 4](https://factorio.kalzumeus.com/tech/biotech-machines-mk04.md) ### Incubator MK 04 (`incubator-mk04`) - 1 s · tier 10 - Ingredients: 30 × [Wall shield](https://factorio.kalzumeus.com/item/wall-shield.md), 1 × [Incubator MK 03](https://factorio.kalzumeus.com/item/incubator-mk03.md), 10 × [Control unit](https://factorio.kalzumeus.com/item/control-unit.md), 20 × [Boron carbide](https://factorio.kalzumeus.com/item/boron-carbide.md), 20 × [Super alloy](https://factorio.kalzumeus.com/item/super-alloy.md), 5 × [Blanket](https://factorio.kalzumeus.com/item/blanket.md), 50 × [Iron niobium alloy](https://factorio.kalzumeus.com/item/nbfe-alloy.md), 80 × [Neodymium magnet](https://factorio.kalzumeus.com/item/re-magnet.md), 4 × [Metastable Quasicrystal](https://factorio.kalzumeus.com/item/metastable-quasicrystal.md), 1 × [Superconducting Claw-pole Engine](https://factorio.kalzumeus.com/item/sc-engine.md), 1 × [Mechanical Parts 04](https://factorio.kalzumeus.com/item/mechanical-parts-04.md) - Results: 1 × [Incubator MK 04](https://factorio.kalzumeus.com/item/incubator-mk04.md) - Made in: Burner assembling machine MK 01, Burner assembling machine MK 02, Burner assembling machine MK 03, Automated factory MK 01, Automated factory MK 02, Automated factory MK 03, Automated factory MK 04, Character, Character (flying), Mutagenic infusion, (flying) - Unlocked by: [Biotechnology machines - Stage 4](https://factorio.kalzumeus.com/tech/biotech-machines-mk04.md) ### Microorganism mine MK 04 (`micro-mine-mk04`) - 4 s · tier 10 - Ingredients: 1 × [Microorganism mine MK 03](https://factorio.kalzumeus.com/item/micro-mine-mk03.md), 30 × [Advanced coating](https://factorio.kalzumeus.com/item/science-coating.md), 5 × [Divertor](https://factorio.kalzumeus.com/item/divertor.md), 30 × [Control unit](https://factorio.kalzumeus.com/item/control-unit.md), 20 × [Metallic glass](https://factorio.kalzumeus.com/item/metallic-glass.md), 30 × [Boron carbide](https://factorio.kalzumeus.com/item/boron-carbide.md), 30 × [Hyperelastic material](https://factorio.kalzumeus.com/item/hyperelastic-material.md), 100 × [Phosphate glass](https://factorio.kalzumeus.com/item/phosphate-glass.md), 5 × [Metastable Quasicrystal](https://factorio.kalzumeus.com/item/metastable-quasicrystal.md), 1 × [Superconducting Claw-pole Engine](https://factorio.kalzumeus.com/item/sc-engine.md), 1 × [Mechanical Parts 04](https://factorio.kalzumeus.com/item/mechanical-parts-04.md) - Results: 1 × [Microorganism mine MK 04](https://factorio.kalzumeus.com/item/micro-mine-mk04.md) - Made in: Burner assembling machine MK 01, Burner assembling machine MK 02, Burner assembling machine MK 03, Automated factory MK 01, Automated factory MK 02, Automated factory MK 03, Automated factory MK 04, Character, Character (flying), Mutagenic infusion, (flying) - Unlocked by: [Biotechnology machines - Stage 4](https://factorio.kalzumeus.com/tech/biotech-machines-mk04.md) ### Phytoplankton farm MK 04 (`plankton-farm-mk04`) - 4 s · tier 10 - Ingredients: 1 × [Phytoplankton farm MK 03](https://factorio.kalzumeus.com/item/plankton-farm-mk03.md), 5 × [Wall shield](https://factorio.kalzumeus.com/item/wall-shield.md), 2 × [Advanced coating](https://factorio.kalzumeus.com/item/science-coating.md), 5 × [Intelligent unit](https://factorio.kalzumeus.com/item/intelligent-unit.md), 5 × [Superconductor servomechanisms](https://factorio.kalzumeus.com/item/superconductor-servomechanims.md), 10 × [Harmonic absorber](https://factorio.kalzumeus.com/item/harmonic-absorber.md), 7 × [Metastable Quasicrystal](https://factorio.kalzumeus.com/item/metastable-quasicrystal.md), 2 × [Superconducting Claw-pole Engine](https://factorio.kalzumeus.com/item/sc-engine.md), 1 × [Mechanical Parts 04](https://factorio.kalzumeus.com/item/mechanical-parts-04.md) - Results: 1 × [Phytoplankton farm MK 04](https://factorio.kalzumeus.com/item/plankton-farm-mk04.md) - Made in: Burner assembling machine MK 01, Burner assembling machine MK 02, Burner assembling machine MK 03, Automated factory MK 01, Automated factory MK 02, Automated factory MK 03, Automated factory MK 04, Character, Character (flying), Mutagenic infusion, (flying) - Unlocked by: [Biotechnology machines - Stage 4](https://factorio.kalzumeus.com/tech/biotech-machines-mk04.md) ### Reproductive complex MK 04 (`rc-mk04`) - 10 s · tier 10 - Ingredients: 1 × [Reproductive complex MK 03](https://factorio.kalzumeus.com/item/rc-mk03.md), 40 × [Advanced coating](https://factorio.kalzumeus.com/item/science-coating.md), 20 × [Wall shield](https://factorio.kalzumeus.com/item/wall-shield.md), 100 × [Iron niobium alloy](https://factorio.kalzumeus.com/item/nbfe-alloy.md), 200 × [Super alloy](https://factorio.kalzumeus.com/item/super-alloy.md), 40 × [Control unit](https://factorio.kalzumeus.com/item/control-unit.md), 50 × [NENBIT matrix](https://factorio.kalzumeus.com/item/nenbit-matrix.md), 30 × [Silver foam](https://factorio.kalzumeus.com/item/silver-foam.md), 30 × [Metallic glass](https://factorio.kalzumeus.com/item/metallic-glass.md), 100 × [Low density structure](https://factorio.kalzumeus.com/item/low-density-structure.md), 20 × [Intelligent unit](https://factorio.kalzumeus.com/item/intelligent-unit.md), 50 × [Hyperelastic material](https://factorio.kalzumeus.com/item/hyperelastic-material.md), 150 × [Phosphate glass](https://factorio.kalzumeus.com/item/phosphate-glass.md), 6 × [Metastable Quasicrystal](https://factorio.kalzumeus.com/item/metastable-quasicrystal.md), 3 × [Superconducting Claw-pole Engine](https://factorio.kalzumeus.com/item/sc-engine.md), 12 × [Mechanical Parts 04](https://factorio.kalzumeus.com/item/mechanical-parts-04.md) - Results: 1 × [Reproductive complex MK 04](https://factorio.kalzumeus.com/item/rc-mk04.md) - Made in: Burner assembling machine MK 01, Burner assembling machine MK 02, Burner assembling machine MK 03, Automated factory MK 01, Automated factory MK 02, Automated factory MK 03, Automated factory MK 04, Character, Character (flying), Mutagenic infusion, (flying) - Unlocked by: [Biotechnology machines - Stage 4](https://factorio.kalzumeus.com/tech/biotech-machines-mk04.md) ### Research center MK 04 (`research-center-mk04`) - 4 s · tier 10 - Ingredients: 1 × [Research center MK 03](https://factorio.kalzumeus.com/item/research-center-mk03.md), 30 × [Wall shield](https://factorio.kalzumeus.com/item/wall-shield.md), 15 × [Control unit](https://factorio.kalzumeus.com/item/control-unit.md), 25 × [Boron carbide](https://factorio.kalzumeus.com/item/boron-carbide.md), 20 × [Low density structure](https://factorio.kalzumeus.com/item/low-density-structure.md), 5 × [Blanket](https://factorio.kalzumeus.com/item/blanket.md), 50 × [Iron niobium alloy](https://factorio.kalzumeus.com/item/nbfe-alloy.md), 10 × [Quantum vortex storage system](https://factorio.kalzumeus.com/item/quantum-vortex-storage-system.md), 100 × [Aerogel](https://factorio.kalzumeus.com/item/aerogel.md), 50 × [Intelligent unit](https://factorio.kalzumeus.com/item/intelligent-unit.md), 8 × [Metastable Quasicrystal](https://factorio.kalzumeus.com/item/metastable-quasicrystal.md), 2 × [Superconducting Claw-pole Engine](https://factorio.kalzumeus.com/item/sc-engine.md), 1 × [Mechanical Parts 04](https://factorio.kalzumeus.com/item/mechanical-parts-04.md) - Results: 1 × [Research center MK 04](https://factorio.kalzumeus.com/item/research-center-mk04.md) - Made in: Burner assembling machine MK 01, Burner assembling machine MK 02, Burner assembling machine MK 03, Automated factory MK 01, Automated factory MK 02, Automated factory MK 03, Automated factory MK 04, Character, Character (flying), Mutagenic infusion, (flying) - Unlocked by: [Biotechnology machines - Stage 4](https://factorio.kalzumeus.com/tech/biotech-machines-mk04.md) ### Slaughterhouse MK 04 (`slaughterhouse-mk04`) - 1 s · tier 10 - Ingredients: 5 × [Blanket](https://factorio.kalzumeus.com/item/blanket.md), 20 × [Wall shield](https://factorio.kalzumeus.com/item/wall-shield.md), 40 × [Iron niobium alloy](https://factorio.kalzumeus.com/item/nbfe-alloy.md), 100 × [Super steel](https://factorio.kalzumeus.com/item/super-steel.md), 10 × [Control unit](https://factorio.kalzumeus.com/item/control-unit.md), 1 × [Slaughterhouse MK 03](https://factorio.kalzumeus.com/item/slaughterhouse-mk03.md), 20 × [Nanoelectromechanical systems](https://factorio.kalzumeus.com/item/nems.md), 60 × [Sub denier microfiber](https://factorio.kalzumeus.com/item/sub-denier-microfiber.md), 8 × [Metastable Quasicrystal](https://factorio.kalzumeus.com/item/metastable-quasicrystal.md), 3 × [Superconducting Claw-pole Engine](https://factorio.kalzumeus.com/item/sc-engine.md), 1 × [Mechanical Parts 04](https://factorio.kalzumeus.com/item/mechanical-parts-04.md) - Results: 1 × [Slaughterhouse MK 04](https://factorio.kalzumeus.com/item/slaughterhouse-mk04.md) - Made in: Burner assembling machine MK 01, Burner assembling machine MK 02, Burner assembling machine MK 03, Automated factory MK 01, Automated factory MK 02, Automated factory MK 03, Automated factory MK 04, Character, Character (flying), Mutagenic infusion, (flying) - Unlocked by: [Biotechnology machines - Stage 4](https://factorio.kalzumeus.com/tech/biotech-machines-mk04.md)